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Single-Cell Analysis of Ribonucleotide Reductase Transcriptional and Translational Response to DNA Damage

The ribonucleotide reductase (RNR) enzyme catalyzes an essential step in the production of deoxyribonucleotide triphosphates (dNTPs) in cells. Bulk biochemical measurements in synchronized Saccharomyces cerevisiae cells suggest that RNR mRNA production is maximal in late G(1) and S phases; however,...

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Bibliografiska uppgifter
Huvudupphovsmän: Mazumder, Aprotim, Tummler, Katja, Bathe, Mark, Samson, Leona D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554213/
https://ncbi.nlm.nih.gov/pubmed/23184665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01020-12
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