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The Type ISP Restriction–Modification enzymes LlaBIII and LlaGI use a translocation–collision mechanism to cleave non-specific DNA distant from their recognition sites

The Type ISP Restriction–Modification (RM) enzyme LlaBIII is encoded on plasmid pJW566 and can protect Lactococcus lactis strains against bacteriophage infections in milk fermentations. It is a single polypeptide RM enzyme comprising Mrr endonuclease, DNA helicase, adenine methyltransferase and targ...

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Bibliografiske detaljer
Main Authors: Šišáková, Eva, van Aelst, Kara, Diffin, Fiona M., Szczelkun, Mark D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553950/
https://ncbi.nlm.nih.gov/pubmed/23222132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1209
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