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The single polypeptide restriction–modification enzyme LlaGI is a self-contained molecular motor that translocates DNA loops

To cleave DNA, the single polypeptide restriction–modification enzyme LlaGI must communicate between a pair of indirectly repeated recognition sites. We demonstrate that this communication occurs by a 1-dimensional route, namely unidirectional dsDNA loop translocation rightward of the specific recog...

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Bibliografiske detaljer
Main Authors: Smith, Rachel M., Josephsen, Jytte, Szczelkun, Mark D.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790907/
https://ncbi.nlm.nih.gov/pubmed/19783815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp794
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