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An Mrr-family nuclease motif in the single polypeptide restriction–modification enzyme LlaGI

Bioinformatic analysis of the putative nuclease domain of the single polypeptide restriction–modification enzyme LlaGI reveals amino acid motifs characteristic of the Escherichia coli methylated DNA-specific Mrr endonuclease. Using mutagenesis, we examined the role of the conserved residues in both...

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Detalles Bibliográficos
Main Authors: Smith, Rachel M., Josephsen, Jytte, Szczelkun, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790908/
https://ncbi.nlm.nih.gov/pubmed/19793866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp795
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