Anti-prion activity of an RNA aptamer and its structural basis

Prion proteins (PrPs) cause prion diseases, such as bovine spongiform encephalopathy. The conversion of a normal cellular form (PrP(C)) of PrP into an abnormal form (PrP(Sc)) is thought to be associated with the pathogenesis. An RNA aptamer that tightly binds to and stabilizes PrP(C) is expected to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mashima, Tsukasa, Nishikawa, Fumiko, Kamatari, Yuji O., Fujiwara, Hiromichi, Saimura, Masayuki, Nagata, Takashi, Kodaki, Tsutomu, Nishikawa, Satoshi, Kuwata, Kazuo, Katahira, Masato
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Structural Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553944/
https://ncbi.nlm.nih.gov/pubmed/23180780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1132
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak