Anti-prion activity of an RNA aptamer and its structural basis

Prion proteins (PrPs) cause prion diseases, such as bovine spongiform encephalopathy. The conversion of a normal cellular form (PrP(C)) of PrP into an abnormal form (PrP(Sc)) is thought to be associated with the pathogenesis. An RNA aptamer that tightly binds to and stabilizes PrP(C) is expected to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mashima, Tsukasa, Nishikawa, Fumiko, Kamatari, Yuji O., Fujiwara, Hiromichi, Saimura, Masayuki, Nagata, Takashi, Kodaki, Tsutomu, Nishikawa, Satoshi, Kuwata, Kazuo, Katahira, Masato
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553944/
https://ncbi.nlm.nih.gov/pubmed/23180780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1132
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados