Loading...

Unique quadruplex structure and interaction of an RNA aptamer against bovine prion protein

RNA aptamers against bovine prion protein (bPrP) were obtained, most of the obtained aptamers being found to contain the r(GGAGGAGGAGGA) (R12) sequence. Then, it was revealed that R12 binds to both bPrP and its β-isoform with high affinity. Here, we present the structure of R12. This is the first re...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Mashima, Tsukasa, Matsugami, Akimasa, Nishikawa, Fumiko, Nishikawa, Satoshi, Katahira, Masato
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764455/
https://ncbi.nlm.nih.gov/pubmed/19666719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp647
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!