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Binding of an RNA aptamer and a partial peptide of a prion protein: crucial importance of water entropy in molecular recognition

It is a central issue to elucidate the new type of molecular recognition accompanied by a global structural change of a molecule upon binding to its targets. Here we investigate the driving force for the binding of R12 (a ribonucleic acid aptamer) and P16 (a partial peptide of a prion protein) durin...

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Bibliografiske detaljer
Main Authors: Hayashi, Tomohiko, Oshima, Hiraku, Mashima, Tsukasa, Nagata, Takashi, Katahira, Masato, Kinoshita, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066790/
https://ncbi.nlm.nih.gov/pubmed/24803670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku382
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