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Activation of the Nlrp1b Inflammasome by Reduction of Cytosolic ATP

The efficacy of the innate immune system depends on its ability to mount an appropriate response to diverse infections and damaging agents. Key components of this system are pattern recognition receptors that detect pathogen-associated and damage-associated molecular patterns (PAMPs and DAMPs). Nlrp...

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Bibliographic Details
Main Authors: Liao, Kuo-Chieh, Mogridge, Jeremy
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553809/
https://ncbi.nlm.nih.gov/pubmed/23230290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01003-12
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