Listeria monocytogenes and Shigella flexneri Activate the NLRP1B Inflammasome

Activation of the innate immune receptor NLRP1B leads to the formation of an inflammasome, which induces autoproteolytic processing of pro-caspase-1, and ultimately to the release of inflammatory cytokines and to the execution of pyroptosis. One of the signals to which NLRP1B responds is metabolic s...

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Udgivet i:Infect Immun
Main Authors: Neiman-Zenevich, Jana, Stuart, Sarah, Abdel-Nour, Mena, Girardin, Stephen E., Mogridge, Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649023/
https://ncbi.nlm.nih.gov/pubmed/28808162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00338-17
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