Capsular Polysaccharide Is Involved in NLRP3 Inflammasome Activation by Klebsiella pneumoniae Serotype K1

Klebsiella pneumoniae (strain 43816, K2 serotype) induces interleukin-1β (IL-1β) secretion, but neither the bacterial factor triggering the activation of these inflammasome-dependent responses nor whether they are mediated by NLRP3 or NLRC4 is known. In this study, we identified a capsular polysacch...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Hua, Kuo-Feng, Yang, Feng-Ling, Chiu, Hsiao-Wen, Chou, Ju-Ching, Dong, Wei-Chih, Lin, Chien-Nan, Lin, Chai-Yi, Wang, Jin-Town, Li, Lan-Hui, Chiu, Huan-Wen, Chiu, Yi-Chich, Wu, Shih-Hsiung
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534678/
https://ncbi.nlm.nih.gov/pubmed/26077758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00125-15
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