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HIV-1 Subtype Is an Independent Predictor of Reverse Transcriptase Mutation K65R in HIV-1 Patients Treated with Combination Antiretroviral Therapy Including Tenofovir

Subtype-dependent selection of HIV-1 reverse transcriptase resistance mutation K65R was previously observed in cell culture and small clinical investigations. We compared K65R prevalence across subtypes A, B, C, F, G, and CRF02_AG separately in a cohort of 3,076 patients on combination therapy inclu...

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Détails bibliographiques
Auteurs principaux: Theys, K., Vercauteren, J., Snoeck, J., Zazzi, M., Camacho, R. J., Torti, C., Schülter, E., Clotet, B., Sönnerborg, A., De Luca, A., Grossman, Z., Struck, D., Vandamme, A.-M., Abecasis, A. B.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553726/
https://ncbi.nlm.nih.gov/pubmed/23183438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01668-12
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