International Cohort Analysis of the Antiviral Activities of Zidovudine and Tenofovir in the Presence of the K65R Mutation in Reverse Transcriptase

A K65R mutation in HIV-1 reverse transcriptase can occur with the failure of tenofovir-, didanosine-, abacavir-, and, in some cases, stavudine-containing regimens and leads to reduced phenotypic susceptibility to these drugs and hypersusceptibility to zidovudine, but its clinical impact is poorly de...

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Detalles Bibliográficos
Main Authors: Grant, Philip M., Taylor, Jonathan, Nevins, Andrew B., Calvez, Vincent, Marcelin, Anne-Geneviève, Wirden, Marc, Zolopa, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849386/
https://ncbi.nlm.nih.gov/pubmed/20124005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01380-09
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