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Decreasing population selection rates of resistance mutation K65R over time in HIV-1 patients receiving combination therapy including tenofovir

OBJECTIVES: The use of tenofovir is highly associated with the emergence of mutation K65R, which confers broad resistance to nucleoside/nucleotide analogue reverse transcriptase inhibitors (NRTIs), especially when tenofovir is combined with other NRTIs also selecting for K65R. Although recent HIV-1...

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Detalhes bibliográficos
Main Authors: Theys, K., Snoeck, J., Vercauteren, J., Abecasis, A. B., Vandamme, A.-M., Camacho, R. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543118/
https://ncbi.nlm.nih.gov/pubmed/23027713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks380
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