Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding

The budding yeast Sir2 (silent information regulator 2) protein is the founding member of the sirtuin family of NAD-dependent histone/protein deacetylases. Its function in transcriptional silencing requires both the highly conserved catalytic domain and a poorly understood N-terminal regulatory doma...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hsu, Hao-Chi, Wang, Chia-Lin, Wang, Mingzhu, Yang, Na, Chen, Zhi, Sternglanz, Rolf, Xu, Rui-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2013
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553284/
https://ncbi.nlm.nih.gov/pubmed/23307867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.208140.112
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker