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Importance of the Sir3 N Terminus and Its Acetylation for Yeast Transcriptional Silencing

The N-terminal alanine residues of the silencing protein Sir3 and of Orc1 are acetylated by the NatA N(α)-acetyltransferase. Mutations demonstrate that the N terminus of Sir3 is important for its function. Sir3 and, perhaps, also Orc1 are the NatA substrates whose lack of acetylation in ard1 and nat...

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Hlavní autoři: Wang, Xiaorong, Connelly, Jessica J., Wang, Chia-Lin, Sternglanz, Rolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448112/
https://ncbi.nlm.nih.gov/pubmed/15454564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.028803
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