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Downregulation of Cdc6 and pre-replication complexes in response to methionine stress in breast cancer cells
Methionine and homocysteine are metabolites in the transmethylation pathway leading to synthesis of the methyl-donor S-adenosylmethionine (SAM). Most cancer cells stop proliferating during methionine stress conditions, when methionine is replaced in the growth media by its immediate metabolic precur...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552924/ https://ncbi.nlm.nih.gov/pubmed/23159852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22767 |
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