Lipid remodeling in response to methionine stress in MDA-MBA-468 triple-negative breast cancer cells

Methionine (Met) is an essential amino acid and critical precursor to the cellular methyl donor S-adenosylmethionine. Unlike nontransformed cells, cancer cells have a unique metabolic requirement for Met and are unable to proliferate in growth media where Met is replaced with its metabolic precursor...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Borrego, Stacey L., Fahrmann, Johannes, Hou, Jue, Lin, Da-Wei, Tromberg, Bruce J., Fiehn, Oliver, Kaiser, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8042402/
https://ncbi.nlm.nih.gov/pubmed/33647277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jlr.2021.100056
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