Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells

BACKGROUND: The majority of cancer cells have a unique metabolic requirement for methionine that is not observed in normal, non-tumorigenic cells. This phenotype is described as “methionine dependence” or “methionine stress sensitivity” in which cancer cells are unable to proliferate when methionine...

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Bibliografiske detaljer
Udgivet i:Cancer Metab
Main Authors: Borrego, Stacey L., Fahrmann, Johannes, Datta, Rupsa, Stringari, Chiara, Grapov, Dmitry, Zeller, Michael, Chen, Yumay, Wang, Ping, Baldi, Pierre, Gratton, Enrico, Fiehn, Oliver, Kaiser, Peter
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852440/
https://ncbi.nlm.nih.gov/pubmed/27141305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-016-0148-6
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