Mitochondria “fuel” breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

Here, we present new genetic and morphological evidence that human tumors consist of two distinct metabolic compartments. First, re-analysis of genome-wide transcriptional profiling data revealed that > 95 gene transcripts associated with mitochondrial biogenesis and/or mitochondrial translation...

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Detalhes bibliográficos
Main Authors: Sotgia, Federica, Whitaker-Menezes, Diana, Martinez-Outschoorn, Ubaldo E., Salem, Ahmed F., Tsirigos, Aristotelis, Lamb, Rebecca, Sneddon, Sharon, Hulit, James, Howell, Anthony, Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552922/
https://ncbi.nlm.nih.gov/pubmed/23172368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22777
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