Mitochondria “fuel” breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

Here, we present new genetic and morphological evidence that human tumors consist of two distinct metabolic compartments. First, re-analysis of genome-wide transcriptional profiling data revealed that > 95 gene transcripts associated with mitochondrial biogenesis and/or mitochondrial translation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sotgia, Federica, Whitaker-Menezes, Diana, Martinez-Outschoorn, Ubaldo E., Salem, Ahmed F., Tsirigos, Aristotelis, Lamb, Rebecca, Sneddon, Sharon, Hulit, James, Howell, Anthony, Lisanti, Michael P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2012
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552922/
https://ncbi.nlm.nih.gov/pubmed/23172368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22777
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