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Oral Thrombostatin FM19 Inhibits Prostate Cancer
Thrombin stimulates proliferation, invasion and metastasis by cleaving PAR1 on a human prostate cancer cells. Current direct thrombin inhibitors pose risks for bleeding in the cancer patients. We have developed an oral reversible direct thrombin inhibitor called FM19. FM19 inhibits thrombin-induced...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3552554/ https://ncbi.nlm.nih.gov/pubmed/20886199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH09-08-0570 |
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