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ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17

The respiratory epithelium is subject to continuous environmental stress and its responses to injury or infection are largely mediated by transactivation of the epidermal growth factor receptor (EGFR) and downstream signaling cascades. Based on previous studies indicating involvement of ATP-dependen...

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Autors principals: Sham, Derek, Wesley, Umadevi V., Hristova, Milena, van der Vliet, Albert
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548788/
https://ncbi.nlm.nih.gov/pubmed/23349873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054391
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