ATP-mediated Activation of the NADPH Oxidase DUOX1 Mediates Airway Epithelial Responses to Bacterial Stimuli

Activation of the NADPH oxidase homolog dual oxidase 1 (DUOX1) within the airway epithelium represents a key mechanism of innate airway host defense, through enhanced production of H(2)O(2), which mediates cellular signaling pathways that regulate the production of various inflammatory mediators. Pr...

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Detalhes bibliográficos
Main Authors: Boots, Agnes W., Hristova, Milena, Kasahara, David I., Haenen, Guido R. M. M., Bast, Aalt, van der Vliet, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719424/
https://ncbi.nlm.nih.gov/pubmed/19386603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809761200
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