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Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells

Duox NADPH oxidases generate hydrogen peroxide at the air-liquid interface of the respiratory tract and at apical membranes of thyroid follicular cells. Inactivating mutations of Duox2 have been linked to congenital hypothyroidism, and epigenetic silencing of Duox is frequently observed in lung canc...

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Autori principali: Luxen, Sylvia, Noack, Deborah, Frausto, Monika, Davanture, Suzel, Torbett, Bruce E., Knaus, Ulla G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714442/
https://ncbi.nlm.nih.gov/pubmed/19339556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.044123
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