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ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17

The respiratory epithelium is subject to continuous environmental stress and its responses to injury or infection are largely mediated by transactivation of the epidermal growth factor receptor (EGFR) and downstream signaling cascades. Based on previous studies indicating involvement of ATP-dependen...

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Detalhes bibliográficos
Main Authors: Sham, Derek, Wesley, Umadevi V., Hristova, Milena, van der Vliet, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548788/
https://ncbi.nlm.nih.gov/pubmed/23349873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054391
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