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ATP-Mediated Transactivation of the Epidermal Growth Factor Receptor in Airway Epithelial Cells Involves DUOX1-Dependent Oxidation of Src and ADAM17

The respiratory epithelium is subject to continuous environmental stress and its responses to injury or infection are largely mediated by transactivation of the epidermal growth factor receptor (EGFR) and downstream signaling cascades. Based on previous studies indicating involvement of ATP-dependen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sham, Derek, Wesley, Umadevi V., Hristova, Milena, van der Vliet, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548788/
https://ncbi.nlm.nih.gov/pubmed/23349873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054391
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