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Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart

AIMS: Impaired energy metabolism has been implicated in the pathogenesis of heart failure. Hyperpolarized (13)C magnetic resonance (MR), in which (13)C-labelled metabolites are followed using MR imaging (MRI) or spectroscopy (MRS), has enabled non-invasive assessment of pyruvate metabolism. We inves...

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書誌詳細
主要な著者: Schroeder, Marie A., Lau, Angus Z., Chen, Albert P., Gu, Yiping, Nagendran, Jeevan, Barry, Jennifer, Hu, Xudong, Dyck, Jason R.B., Tyler, Damian J., Clarke, Kieran, Connelly, Kim A., Wright, Graham A., Cunningham, Charles H.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547367/
https://ncbi.nlm.nih.gov/pubmed/23258802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurjhf/hfs192
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