Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart

AIMS: Impaired energy metabolism has been implicated in the pathogenesis of heart failure. Hyperpolarized (13)C magnetic resonance (MR), in which (13)C-labelled metabolites are followed using MR imaging (MRI) or spectroscopy (MRS), has enabled non-invasive assessment of pyruvate metabolism. We inves...

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Detaylı Bibliyografya
Asıl Yazarlar: Schroeder, Marie A., Lau, Angus Z., Chen, Albert P., Gu, Yiping, Nagendran, Jeevan, Barry, Jennifer, Hu, Xudong, Dyck, Jason R.B., Tyler, Damian J., Clarke, Kieran, Connelly, Kim A., Wright, Graham A., Cunningham, Charles H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2013
Konular:
Experimental
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547367/
https://ncbi.nlm.nih.gov/pubmed/23258802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurjhf/hfs192
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