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A HaloTag-Based Small Molecule Microarray Screening Methodology with Increased Sensitivity and Multiplex Capabilities

[Image: see text] Small Molecule Microarrays (SMMs) represent a general platform for screening small molecule–protein interactions independent of functional inhibition of target proteins. In an effort to increase the scope and utility of SMMs, we have modified the SMM screening methodology to increa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Noblin, Devin J., Page, Charlotte M., Tae, Hyun Seop, Gareiss, Peter C., Schneekloth, John S., Crews, Craig M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547077/
https://ncbi.nlm.nih.gov/pubmed/23013033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300453k
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