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Marked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [(11)C]ABP688 positron emission tomography
Nicotine addiction is a major public health problem, resulting in primary glutamatergic dysfunction. We measured the glutamate receptor binding in the human brain and provided direct evidence for the abnormal glutamate system in smokers. Because antagonism of the metabotropic glutamate receptor 5 (m...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545768/ https://ncbi.nlm.nih.gov/pubmed/23248277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210984110 |
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