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Marked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [(11)C]ABP688 positron emission tomography
Nicotine addiction is a major public health problem, resulting in primary glutamatergic dysfunction. We measured the glutamate receptor binding in the human brain and provided direct evidence for the abnormal glutamate system in smokers. Because antagonism of the metabotropic glutamate receptor 5 (m...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545768/ https://ncbi.nlm.nih.gov/pubmed/23248277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210984110 |
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