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In vivo and in vitro validation of reference tissue models for the mGluR(5) ligand [(11)C]ABP688

The primary objective of this study was to verify the suitability of reference tissue-based quantification methods of the metabotropic glutamate receptor type 5 (mGluR(5)) with [(11)C]ABP688. This study presents in vivo (Positron Emission Tomography (PET)) and in vitro (autoradiography) measurements...

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Detalhes bibliográficos
Main Authors: Elmenhorst, David, Minuzzi, Luciano, Aliaga, Antonio, Rowley, Jared, Massarweh, Gassan, Diksic, Mirko, Bauer, Andreas, Rosa-Neto, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949244/
https://ncbi.nlm.nih.gov/pubmed/20531460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.65
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