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Reduced Metabotropic Glutamate Receptor 5 Density in Major Depression Determined by [(11)C]ABP688 Positron Emission Tomography and Postmortem Study
OBJECTIVE: Clinical and preclinical evidence suggest a hyperactive glutamatergic system in clinical depression. Recently, the metabotropic glutamate receptor 5 (mGluR5) has been proposed as an attractive target for discovery of novel therapeutic approaches against depression. The goal of this study...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129412/ https://ncbi.nlm.nih.gov/pubmed/21498461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2011.09111607 |
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