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A peptide-based biosensor assay to detect intracellular Syk kinase activation and inhibition()
Spleen Tyrosine Kinase (Syk) has been implicated in a number of pathologies including cancer and rheumatoid arthritis and thus has been pursued as a novel therapeutic target. Because of the complex relationship between Syk’s auto- and other internal phosphorylation sites, scaffolding proteins, enzym...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545090/ https://ncbi.nlm.nih.gov/pubmed/22920457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300970h |
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