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Time-Resolved Luminescence Detection of Syk Kinase Activity Through Terbium Sensitization

Disruption of regulatory protein phosphorylation can lead to disease, and is particularly prevalent in cancers. Inhibitors that target deregulated kinases are therefore a major focus of chemotherapeutic development. Achieving sensitivity and specificity in high-throughput compatible kinase assays is...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lipchik, Andrew M., Parker, Laurie L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632334/
https://ncbi.nlm.nih.gov/pubmed/23414415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3023422
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