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Time-Resolved Luminescence Detection of Syk Kinase Activity Through Terbium Sensitization

Disruption of regulatory protein phosphorylation can lead to disease, and is particularly prevalent in cancers. Inhibitors that target deregulated kinases are therefore a major focus of chemotherapeutic development. Achieving sensitivity and specificity in high-throughput compatible kinase assays is...

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Bibliografske podrobnosti
Main Authors: Lipchik, Andrew M., Parker, Laurie L.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632334/
https://ncbi.nlm.nih.gov/pubmed/23414415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3023422
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