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Time-Resolved Luminescence Detection of Syk Kinase Activity Through Terbium Sensitization

Disruption of regulatory protein phosphorylation can lead to disease, and is particularly prevalent in cancers. Inhibitors that target deregulated kinases are therefore a major focus of chemotherapeutic development. Achieving sensitivity and specificity in high-throughput compatible kinase assays is...

詳細記述

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書誌詳細
主要な著者: Lipchik, Andrew M., Parker, Laurie L.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632334/
https://ncbi.nlm.nih.gov/pubmed/23414415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac3023422
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