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A Time-Resolved Luminescence Biosensor Assay for Anaplastic Lymphoma Kinase (ALK) Activity

A novel time-resolved luminescence biosensor assay for anaplastic lymphoma kinase (ALK) was developed. We used a straightforward strategy to modify a known ALK substrate into a peptide biosensor that can accommodate terbium luminescence sensitization upon its phosphorylation by ALK. Since this strat...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Cui, Wei, Parker, Laurie L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288484/
https://ncbi.nlm.nih.gov/pubmed/25406835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc07453j
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