inv(16)/t(16;16) acute myeloid leukemia with non–type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

The inv(16)(p13q22)/t(16;16)(p13;q22) in acute myeloid leukemia results in multiple CBFB-MYH11 fusion transcripts, with type A being most frequent. The biologic and prognostic implications of different fusions are unclear. We analyzed CBFB-MYH11 fusion types in 208 inv(16)/t(16;16) patients with de...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Schwind, Sebastian, Edwards, Colin G., Nicolet, Deedra, Mrózek, Krzysztof, Maharry, Kati, Wu, Yue-Zhong, Paschka, Peter, Eisfeld, Ann-Kathrin, Hoellerbauer, Pia, Becker, Heiko, Metzeler, Klaus H., Curfman, John, Kohlschmidt, Jessica, Prior, Thomas W., Kolitz, Jonathan E., Blum, William, Pettenati, Mark J., Dal Cin, Paola, Carroll, Andrew J., Caligiuri, Michael A., Larson, Richard A., Volinia, Stefano, Marcucci, Guido, Bloomfield, Clara D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2013
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544117/
https://ncbi.nlm.nih.gov/pubmed/23160462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-442772
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky