inv(16)/t(16;16) acute myeloid leukemia with non–type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

The inv(16)(p13q22)/t(16;16)(p13;q22) in acute myeloid leukemia results in multiple CBFB-MYH11 fusion transcripts, with type A being most frequent. The biologic and prognostic implications of different fusions are unclear. We analyzed CBFB-MYH11 fusion types in 208 inv(16)/t(16;16) patients with de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schwind, Sebastian, Edwards, Colin G., Nicolet, Deedra, Mrózek, Krzysztof, Maharry, Kati, Wu, Yue-Zhong, Paschka, Peter, Eisfeld, Ann-Kathrin, Hoellerbauer, Pia, Becker, Heiko, Metzeler, Klaus H., Curfman, John, Kohlschmidt, Jessica, Prior, Thomas W., Kolitz, Jonathan E., Blum, William, Pettenati, Mark J., Dal Cin, Paola, Carroll, Andrew J., Caligiuri, Michael A., Larson, Richard A., Volinia, Stefano, Marcucci, Guido, Bloomfield, Clara D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2013
Pynciau:
Myeloid Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544117/
https://ncbi.nlm.nih.gov/pubmed/23160462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-442772
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