Chronic Caloric Restriction Preserves Mitochondrial Function in Senescence Without Increasing Mitochondrial Biogenesis

Caloric restriction (CR) mitigates many detrimental effects of aging and prolongs lifespan. CR has been suggested to increase mitochondrial biogenesis, thereby attenuating age-related declines in mitochondrial function; a concept that is challenged by recent studies. Here we show that lifelong CR in...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Lanza, Ian R., Zabielski, Piotrek, Klaus, Katherine A., Morse, Dawn M., Heppelmann, Carrie J., Bergen, H. Robert, Dasari, Surendra, Walrand, Stephane, Short, Kevin R., Johnson, Matthew L., Robinson, Matthew M., Schimke, Jill M., Jakaitis, Daniel R., Asmann, Yan W., Sun, Zhifu, Nair, K. Sreekumaran
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544078/
https://ncbi.nlm.nih.gov/pubmed/23217257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.11.003
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki