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Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction
It is known that loss-of-function mutations in the gene encoding Parkin lead to development of Parkinson disease. Recently, Parkin was found to play an important role in the removal of dysfunctional mitochondria via autophagy in neurons. Although Parkin is expressed in the heart, its functional role...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543040/ https://ncbi.nlm.nih.gov/pubmed/23152496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.411363 |
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