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Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes

The Bcl2/adenovirus E1B 19-kDa interacting protein 3 (Bnip3) is an atypical BH3-only protein that is associated with mitochondrial dysfunction and cell death. Bnip3 is also a potent inducer of mitochondrial autophagy, and in this study we have investigated the mechanisms by which Bnip3 induces autop...

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Detalhes bibliográficos
Main Authors: Lee, Youngil, Lee, Hwa-Youn, Hanna, Rita A., Gustafsson, Åsa B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213962/
https://ncbi.nlm.nih.gov/pubmed/21890690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00368.2011
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