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Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore

Bnip3 is a pro-apoptotic BH3-only protein which is associated with mitochondrial dysfunction and cell death. Bnip3 is also a potent inducer of autophagy in many cells. In this study, we have investigated the mechanism by which Bnip3 induces autophagy in adult cardiac myocytes. Overexpression of Bnip...

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Autori principali: Quinsay, Melissa N, Thomas, Robert L, Lee, Youngil, Gustafsson, Åsa B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039735/
https://ncbi.nlm.nih.gov/pubmed/20668412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.7.13005
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