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Bnip3 Mediates Permeabilization of Mitochondria and Release of Cytochrome c via a Novel Mechanism

Bnip3 is a member of the BH3-only subfamily of pro-apoptotic Bcl-2 proteins and is associated with loss of cardiac myocytes after a myocardial infarction. Previous studies have demonstrated that Bnip3 induces mitochondrial dysfunction, but the mechanisms involved in this process remain unknown. In t...

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Detalhes bibliográficos
Main Authors: Quinsay, Melissa N., Lee, Youngil, Rikka, Shivaji, Sayen, M. Richard, Molkentin, Jeffery D., Gottlieb, Roberta A., Gustafsson, Åsa B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866782/
https://ncbi.nlm.nih.gov/pubmed/20025887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.12.004
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