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Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy

Autophagy plays an important role in cellular quality control and is responsible for removing protein aggregates and dysfunctional organelles. Bnip3 is an atypical BH3-only protein that is known to cause mitochondrial dysfunction and cell death. Interestingly, Bnip3 can also protect against cell dea...

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Detalhes bibliográficos
Main Authors: Hanna, Rita A., Quinsay, Melissa N., Orogo, Amabel M., Giang, Kayla, Rikka, Shivaji, Gustafsson, Åsa B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365942/
https://ncbi.nlm.nih.gov/pubmed/22505714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322933
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