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Bnip3 impairs mitochondrial bioenergetics and stimulates mitochondrial turnover

Bnip3 (Bcl-2/adenovirus E1B 19-kDa-interacting protein 3) is a mitochondrial BH3-only protein that contributes to cell death through activation of the mitochondrial pathway of apoptosis. Bnip3 is also known to induce autophagy, but the functional role of autophagy is unclear. In this study, we inves...

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Main Authors: Rikka, S, Quinsay, M N, Thomas, R L, Kubli, D A, Zhang, X, Murphy, A N, Gustafsson, Å B
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058880/
https://ncbi.nlm.nih.gov/pubmed/21278801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.146
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