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Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak
Bnip3 is a pro-apoptotic member of the Bcl-2 family that is down-regulated in pancreatic cancers, which correlates with resistance to chemotherapy and a worsened prognosis. In contrast, Bnip3 is up-regulated in heart failure and contributes to loss of myocardial cells during I/R (ischaemia/reperfusi...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2267317/ https://ncbi.nlm.nih.gov/pubmed/17447897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070319 |
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