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PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes

Myocyte function and survival relies on the maintenance of a healthy population of mitochondria. The PINK1/Parkin pathway plays an important role in clearing defective mitochondria via autophagy in cells. However, how the PINK1/Parkin pathway regulates mitochondrial quality control and whether it co...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kubli, Dieter A., Cortez, Melissa Q., Moyzis, Alexandra G., Najor, Rita H., Lee, Youngil, Gustafsson, Åsa B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482400/
https://ncbi.nlm.nih.gov/pubmed/26110811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130707
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