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Role of Sirtuin 1 in the Regulation of Hepatic Gene Expression by Thyroid Hormone
Sirtuin 1 (SIRT1) is a nuclear deacetylase that modulates lipid metabolism and enhances mitochondrial activity. SIRT1 targets multiple transcription factors and coactivators. Thyroid hormone (T(3)) stimulates the expression of hepatic genes involved in mitochondrial fatty acid oxidation and gluconeo...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543030/ https://ncbi.nlm.nih.gov/pubmed/23209300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.437970 |
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