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Nuclear Corepressors Mediate the Repression of Phospholipase A(2) Group IIa Gene Transcription by Thyroid Hormone

Secretory phospholipase A(2) group IIa (PLA2g2a) is associated with inflammation, hyperlipidemia, and atherogenesis. Transcription of the PLA2g2a gene is induced by multiple cytokines. Here, we report the surprising observation that thyroid hormone (T(3)) inhibited PLA2g2a gene expression in human a...

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Detalhes bibliográficos
Main Authors: Sharma, Pragya, Thakran, Shalini, Deng, Xiong, Elam, Marshall B., Park, Edwards A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675570/
https://ncbi.nlm.nih.gov/pubmed/23629656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445569
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