Role of Sirtuin 1 in the Regulation of Hepatic Gene Expression by Thyroid Hormone

Sirtuin 1 (SIRT1) is a nuclear deacetylase that modulates lipid metabolism and enhances mitochondrial activity. SIRT1 targets multiple transcription factors and coactivators. Thyroid hormone (T(3)) stimulates the expression of hepatic genes involved in mitochondrial fatty acid oxidation and gluconeo...

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Bibliographische Detailangaben
Hauptverfasser: Thakran, Shalini, Sharma, Pragya, Attia, Ramy R., Hori, Roderick T., Deng, Xiong, Elam, Marshall B., Park, Edwards A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543030/
https://ncbi.nlm.nih.gov/pubmed/23209300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.437970
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